« Back
Home /
Avatrombopag

Avatrombopag

Item no.	CS-3397-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	570406-98-3
Available
Alternative Names	AKR-501; E5501; YM477
CAS	570406-98-3
Purity	>98%
Formula	C29H34Cl2N6O3S2
MWt	649.65
Solubility	DMSO : >= 32 mg/mL (49.26 mM)
Clinical Information	Phase 3
Pathway	Immunology/Inflammation
Target	Thrombopoietin Receptor
Biological Activity	Avatrombopag(AKR-501; E5501; YM477) is a novel orally-active thrombopoietin(TPO) receptor agonist with EC50 of 3.3 nM. EC50 value: 3.3 nM [1] Target: TPO receptor agonist in vitro: AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501, however, was shown to be effective only in humans and chimpanzees with high species specificity [1].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CS-3397-10mg-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 10mg

available

Delivery expected until 9/6/2024