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Rasagiline

Rasagiline

Item no.	CS-2901-50mg
Manufacturer	ChemScene
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	136236-51-6
Similar products	136236-51-6
Available
Alternative Names	(R)-AGN1135; TVP1012
CAS	136236-51-6
Purity	>98%
MWt	171.24
Formula	C12H13N
Solubility	DMSO : 100 mg/mL (583.98 mM; Need ultrasonic)
Clinical Information	Launched
Pathway	Neuronal Signaling
Target	Monoamine Oxidase
Biological Activity	Rasagiline (R-AGN1135) is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43?nM and 412?nM for rat brain MAO B and A activity, respectively. In Vitro: Rasagiline (0.25 nM; 96 hours) significantly increases the proliferation rates of SH-SY5Y and 1242-MG upon Dexamethasone (10 uM) treatment. In Vivo: Rasagiline is neuroprotective in a transgenic model of multiple system atrophy. Motor behavioural tests show improvements in motor deficits associated with 2.5 mg/kg Rasagiline therapy.

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Amount: 50mg

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