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(E/Z)-E64FC26

(E/Z)-E64FC26

Item no.	CS-0114217-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	2285446-67-3
Similar products	2285446-67-3
Available
CAS	2285446-67-3
Purity	>98%
MWt	340.38
Formula	C19H23F3O2
Solubility	DMSO : 100 mg/mL (293.79 mM; Need ultrasonic); H2O : < 0.1 mg/mL (insoluble)
Clinical Information	No Development Reported
Pathway	Apoptosis
Target	Apoptosis
Biological Activity	(E/Z)-E64FC26 is a mixture complex of E-E64FC26 and Z-E64FC26. E64FC26 (E-E64FC26) is a potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC₅₀s of 1.9, 20.9, 25.9, 16.3, and 25.4 uM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6. E64FC26 shows anti-myeloma activity^[1]^[2].
Research Area	Cancer

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Amount: 10mg

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Delivery expected until 9/6/2024