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sAJM589

sAJM589

Item no.	CS-0088284-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	2089-82-9
Similar products	2089-82-9
Available
CAS	2089-82-9
Purity	>98%
MWt	246.26
Formula	C16H10N2O
Solubility	DMSO : 5 mg/mL (20.30 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Apoptosis
Target	c-Myc
Biological Activity	sAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC₅₀ of 1.8 uM^[1]. IC50 & Target: IC50: 1.8 uM (Myc)^[1] In Vitro: sAJM589 potently disrupts the Myc-Max heterodimer to reduce Myc protein levels in a dose dependent manner, with an IC₅₀ of 1.8 uM^[1]. sAJM589 suppresses cellular proliferation in diverse Myc-dependent cancer cell lines and anchorage independent growth of Raji cells^[1].
Research Area	Cancer

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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