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ADAMTS-5 Inhibitor

ADAMTS-5 Inhibitor

Item no.	CS-0064746-50mg
Manufacturer	ChemScene
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	929634-33-3
Similar products	929634-33-3
Available
CAS	929634-33-3
Purity	>98%
MWt	449.92
Formula	C16H11ClF3N3OS3
Solubility	DMSO : 83.33 mg/mL (185.21 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Others
Target	Others
Biological Activity	ADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC₅₀ of 1.1 uM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1)^[1]. In Vitro: ADAMTS-5 (aggrecanase-2) is an extracellular matrix-degrading protease implicated in cartilage destruction in arthritis^[2].
Research Area	Inflammation/Immunology

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Amount: 50mg

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Delivery expected until 9/6/2024