MC3482

Item no.	CS-0047672-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Purity	>98%
Formula	C33H38N4O8
MWt	618.68
Solubility	DMSO : >= 130 mg/mL (210.12 mM); H2O : < 0.1 mg/mL (insoluble)
Clinical Information	No Development Reported
Pathway	Epigenetics; Cell Cycle/DNA Damage
Target	Sirtuin; Sirtuin
Biological Activity	MC3482 is a specific sirtuin5 (SIRT5) inhibitor. IC50 & Target: SIRT5^[1] In Vitro: MC3482 inhibits sirtuin5. 50 uM MC3482 inhibits SIRT5 desuccinylating activity without affecting SIRT5 intracellular expression levels. Autophagy and mitophagy increase in SIRT5-silenced cells and in WT cells treated with MC3482 and decrease in SIRT5-overexpressing cells^[1].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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