MIK665

Item no.	CS-0044179-50mg
Manufacturer	ChemScene
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	1799631-75-6
Available
Alternative Names	S-64315
CAS	1799631-75-6
Purity	>98%
Formula	C47H44ClFN6O6S
MWt	875.41
Solubility	H2O : < 0.1 mg/mL (insoluble); DMSO : >= 125 mg/mL (142.79 mM)
Clinical Information	Phase 1
Pathway	Apoptosis
Target	Bcl-2 Family
Biological Activity	MIK665 (S-64315) is a special Mcl-1 inhibitor extracted from patent WO2016207225A1, compound Preparation 13, has an IC₅₀ of 1.81 nM^[1]. IC50 & Target: IC50: 1.81 nM (Mcl-1)^[1] In Vitro: MIK665 (S-64315) inhibits H929 cell with an IC₅₀ of 250 nM^[1].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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