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Finerenone

Finerenone

Item no.	CS-0040097-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	1050477-31-0
Similar products	1050477-31-0
Available
Alternative Names	BAY 94-8862
CAS	1050477-31-0
Purity	>98%
MWt	378.42
Formula	C21H22N4O3
Solubility	10 mM in DMSO
Clinical Information	No Development Reported
Pathway	Metabolic Enzyme/Protease
Target	Mineralocorticoid Receptor
Biological Activity	Finerenone (BAY 94-8862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC₅₀=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease^[1]^[2]. In Vivo: Finerenone (BAY 94-8862) lowers albuminuria by >40% and significantly reduces systolic blood pressure (SBP) in Munich Wistar Frömter (MWF) rat^[1].
Research Area	Cardiovascular Disease

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Amount: 10mg

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Delivery expected until 9/6/2024