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Saredutant

Saredutant

Item no.	CS-0026895-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	142001-63-6
Similar products	142001-63-6
Available
Alternative Names	SR 48968; SR 48968C
CAS	142001-63-6
Purity	>98%
MWt	552.53
Formula	C31H35Cl2N3O2
Solubility	DMSO : 250 mg/mL (452.46 mM; Need ultrasonic)
Clinical Information	Phase 3
Pathway	Neuronal Signaling; GPCR/G Protein
Target	Neurokinin Receptor; Neurokinin Receptor
Biological Activity	Saredutant is a selective NK2 receptor antagonist. IC50 & Target: NK2 receptor^[1] In Vivo: Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with desipramine in an animal model of depression. Saredutant has dose-dependent effects on swim test immobility, with the low dose of 1 mg/kg having no effect and the doses of 3 and 10 mg/kg significantly reducing immobility^[1].
Research Area	Neurological Disease; Endocrinology

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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