Comparison

Tefinostat

Item no. CS-0025742-100mg
Manufacturer ChemScene
Amount 100mg
Category
Type Molecules
Specific against other
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias 914382-60-8
Similar products 914382-60-8
Available
Alternative Names
CHR-2845
CAS
914382-60-8
Purity
>98%
MWt
495.61
Formula
C28H37N3O5
Solubility
DMSO : 100 mg/mL (201.77 mM; Need ultrasonic)
Clinical Information
Phase 2
Pathway
Epigenetics; Cell Cycle/DNA Damage
Target
HDAC; HDAC
Biological Activity
Tefinostat (CHR-2845) is a monocyte/macrophage-targeted pan HDAC inhibitor, cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Anti-monocytoid lineage leukaemias activity[1]. IC50 & Target: HDAC[1]
Research Area
Cancer

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100mg
Available: In stock
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