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Dexanabinol

Dexanabinol

Item no.	CS-0025698-1mg
Manufacturer	ChemScene
Amount	1mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	112924-45-5
Similar products	112924-45-5
Available
Alternative Names	HU-211
CAS	112924-45-5
Purity	>98%
MWt	386.57
Formula	C25H38O3
Solubility	10 mM in DMSO
Clinical Information	Phase 3
Pathway	Immunology/Inflammation; Apoptosis; NF-kappaB
Target	Interleukin Related; TNF Receptor; NF-kappaB
Biological Activity	Dexanabinol (HU-211) is an artificially synthesized cannabinoid derivative and lacks cannabimimetic effects. Dexanabinol exhibits not only the antioxidant and neuroprotective activities in brain but also anti-inflammatory activity by inhibiting NF-kappaB and decreasing cytokines such as TNFalpha and interleukin-6, which could ensure the integrity of BBB and reduce cell apoptosis and death. Dexanabinol is widely used in head injury or stroke treatment and has been shown to be safe in animals and humans^[1].
Research Area	Neurological Disease

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Amount: 1mg

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