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Acevaltrate

Acevaltrate

Item no.	CS-0018575-100mg
Manufacturer	ChemScene
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	25161-41-5
Available
CAS	25161-41-5
Purity	>98%
Formula	C24H32O10
MWt	480.50
Solubility	DMSO : >= 125 mg/mL (260.15 mM)
Clinical Information	No Development Reported
Pathway	Membrane Transporter/Ion Channel
Target	Na+/K+ ATPase
Biological Activity	Acevaltrate, isolated from Valeriana glechomifolia, inhibits the Na⁺/K⁺-ATPase activity in the rat kidney and brain hemispheres with IC₅₀s of 22.8+/-1.1 uM and 42.3+/-1.0 uM, respectively^[1]. IC50 & Target: IC50: 22.8+/-1.1 uM (Na⁺/K⁺-ATPase, in rat kidney), 42.3+/-1.0 uM (Na⁺/K⁺-ATPase, in rat brain hemispheres)^[1] In Vitro: Acevaltrate differentiallys inhibit the activity of rat P-type ATPases in vitro. 60.7+/-7.3% inhibition of the rat H⁺/K⁺-ATPase is achieved at 100 uM^[1].

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