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Cholic acid (sodium)

Cholic acid (sodium)

Item no.	CS-0016849-100mg
Manufacturer	ChemScene
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	361-09-1
Similar products	361-09-1
Available
CAS	361-09-1
Purity	>98%
MWt	430.55
Formula	C24H39NaO5
Solubility	H2O : >= 250 mg/mL (580.65 mM)
Clinical Information	Launched
Pathway	Metabolic Enzyme/Protease
Target	Endogenous Metabolite
Biological Activity	Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. In Vitro: Cholic acid competitively binds Na⁺/taurocholate cotransporting polypeptide (NTCP) on HepG2 cells and significantly inhibits the uptake of Cholic acid (CA)-nanoliposomes (LPs)-Doxorubicin (DOX)-HCl, which indicates that CA-LPs-DOX-HCl are also uptaken via NTCP-mediated endocytosis pathway^[1].
Research Area	Metabolic Disease

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Amount: 100mg

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