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Fluorometholone

Fluorometholone

Item no.	CS-0013955-50mg
Manufacturer	ChemScene
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	426-13-1
Similar products	426-13-1
Available
CAS	426-13-1
Purity	>98%
MWt	376.46
Formula	C22H29FO4
Solubility	10 mM in DMSO
Clinical Information	Launched
Pathway	GPCR/G Protein
Target	Glucocorticoid Receptor
Biological Activity	Fluorometholone, a synthetic glucocorticoid, is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic properties. Fluorometholone can be used for the research of dry eye^[1]. IC50 & Target: glucocorticoid receptor^[1] In Vitro: Fluorometholone (25-100 nM; 12 hours, 24 hours) increases the gene expression of MUC1, MUC4, MUC16 and MUC19 in the conjunctival and corneal epithelial cells through activation of glucocorticoid receptors^[1].
Research Area	Inflammation/Immunology

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50mg

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