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Tocainide (hydrochloride)

Tocainide (hydrochloride)

Item no.	CS-0013838-1mg
Manufacturer	ChemScene
Amount	1mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	71395-14-7
Similar products	71395-14-7
Available
CAS	71395-14-7
Purity	>98%
MWt	228.72
Formula	C11H17ClN2O
Solubility	DMSO : 125 mg/mL (546.52 mM; Need ultrasonic)
Clinical Information	Launched
Pathway	Membrane Transporter/Ion Channel
Target	Sodium Channel
Biological Activity	Tocainide hydrochloride is a sodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is a primary amine analog of lidocaine, can be used for the treatment of tinnitus^[1]^[2]. IC50 & Target: IC50: sodium channel^[1] In Vivo: Tocainide (100 mg/kg) effectively suppresses ventricular ectopic activity in unanesthetized dogs with coronary occlusion. Termination of tocainide infusion in both digitalis toxicity and coronary occlusion models results in prompt return of ventricular ectopic activity^[1].
Research Area	Inflammation/Immunology

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