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Picroside I

Picroside I

Item no.	CS-0008939-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	27409-30-9
Similar products	27409-30-9
Available
Alternative Names	6'-Cinnamoylcatalpol
CAS	27409-30-9
Purity	>98%
MWt	492.47
Formula	C24H28O11
Solubility	H2O : 125 mg/mL (253.82 mM; Need ultrasonic); DMSO : 250 mg/mL (507.65 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	JAK/STAT Signaling; Stem Cell/Wnt
Target	STAT; STAT
Biological Activity	Picroside I is the major ingredient of Picrorhiza kurroa. Picrorhiza kurroa is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II^[1]. Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-gamma^[2].
Research Area	Inflammation/Immunology

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