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5'-Guanylic acid (disodium salt)

5'-Guanylic acid (disodium salt)

Item no.	HY-W010970-100mg
Manufacturer	MedChem Express
CASRN	09.12.5550
Amount	100 mg
Quantity options	100 mg 10mM/1mL 1 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C10H12N5Na2O8P
Citations	[1]Lan T, et al. Type II cGMP-dependent protein kinase phosphorylates EGFR at threonine 669 and thereby inhibits its activation. Biochem Biophys Res Commun. 2019 Aug 6.
Smiles	O=P(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2N=C(N)NC3=O)O1)(O[Na])O[Na]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	5'-GMP (disodium salt); 5'-guanosine monophosphate (disodium salt)
Similar products	09.12.5550
Available
Product Description	5'-Guanylic acid disodium salt (5'-GMP disodium salt) is composed of guanine, ribose, and phosphate moieties and it is a nucleotide monomer in messenger RNA. Guanosine derivatives are involved in intracellular signal transduction and have been identified in repetitive genomic sequences in telomeres, in ribosomal DNA, immunoglobulin heavy‐chain switch regions, and in the control regions of proto-oncogenes[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
MolecularWeight	407.18
Clinical_Information	No Development Reported
Manufacturers Research Area	Others
Solubility	DMSO : < 1 mg/mL (ultrasonic; warming; heat to 80°C)\|H2O : 50 mg/mL (ultrasonic)
Manufacturers Target	Endogenous Metabolite
Isoform	Human Endogenous Metabolite
Pathway	Metabolic Enzyme/Protease

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HY-W010970-100mg-safety-datasheet.pdf