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PF-592379

PF-592379

Item no.	HY-U00400-1mg
Manufacturer	MedChem Express
CASRN	710655-15-5
Amount	1mg
Quantity options	100 mg 10mg 1 ea 1mg 20mg 5mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Attkins N, et al. Pharmacokinetics and elucidation of the rates and routes of N-glucuronidation of PF-592379, an oral dopamine 3 agonist in rat, dog, and human. Xenobiotica. 2010 Nov;40(11):730-42.<br>[2]Wager TT, et al. Dopamine D3/D2 Receptor Antagonist PF-4363467 Attenuates Opioid Drug-Seeking Behavior without Concomitant D2 Side Effects. ACS Chem Neurosci. 2017 Jan 18;8(1):165-177.<br>[3]Collins GT, et al. Lack of abuse potential in a highly selective dopamine D3 agonist, PF-592,379, in drug self-administration and drug discrimination in rats. Behav Pharmacol. 2012 Jun;23(3):280-91.
Smiles	NC1=NC=C([C@@H]2CN(CCC)[C@@H](C)CO2)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	710655-15-5
Available
Product Description	PF-592379 is a potent dopamine D3 receptor agonist with an EC50 of 21 nM.
Shipping	Room temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	235.33
Clinical_Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	10 mM in DMSO
Manufacturers Target	Dopamine Receptor
Isoform	D3 Receptor
Pathway	GPCR/G Protein; Neuronal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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