Item no. |
HY-P0206-25mg |
Manufacturer |
MedChem Express
|
CASRN |
58-82-2 |
Amount |
25 mg |
Quantity options |
100 mg
10mM*1 mL
10 mg
1 mg
25 mg
50 mg
5 mg
|
Category |
|
Type |
Peptides |
Specific against |
other |
Purity |
99.92 |
Formula |
C50H73N15O11 |
Citations |
[1]Hornig B, et al. Role of bradykinin in mediating vascular effects of angiotensin-converting enzyme inhibitors inhumans. Circulation. 1997 Mar 4;95(5):1115-8.<br/>[2]Wang G, et al. Bradykinin stimulates IL-6 production and cell invasion in colorectal cancer cells. Oncol Rep. 2014 Oct;32(4):1709-14.<br/>[3]Dong R, et al. Exogenous Bradykinin Inhibits Tissue Factor Induction and Deep Vein Thrombosis via Activating the eNOS/Phosphoinositide 3-Kinase/Akt Signaling Pathway. Cell Physiol Biochem. 2015;37(4):1592-606.<br/>[4]Uchida S, et al. Afferent fibers involved in the bradykinin-induced cardiovascular reflexes from the ovary in rats. Auton Neurosci. 2015 Dec;193:57-62.<br/>[5]Liu LT, et al. Effect of vascular bradykinin on pancreatic microcirculation and hemorheology in rats with severe acute pancreatitis. Eur Rev Med Pharmacol Sci. 2015;19(14):2646-50. |
Smiles |
O=C(N1[C@@H](CCC1)C(NCC(N[C@H](C(N[C@@H](CO)C(N2[C@@H](CCC2)C(N[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CC3=CC=CC=C3)=O)=O)=O)CC4=CC=CC=C4)=O)=O)[C@H]5N(CCC5)C([C@@H](N)CCCNC(N)=N)=O |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
58-82-2 |
Available |
|
Product Description |
Bradykinin is an effective endothelium-dependent vasodilator that can lower blood pressure. Bradykinin can induce contraction of bronchial and intestinal non-vascular smooth muscle, increase vascular permeability, and participate in the mechanism of pain[1][2][3][4][5]. |
StorageTemperature |
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture) |
Shipping |
Blue Ice |
Manufacturers Applications |
COVID-19-immunoregulation |
MolecularWeight |
1060.21 |
Clinical Information |
Phase 4 |
Manufacturers Research Area |
Cardiovascular Disease; Endocrinology |
Solubility |
10 mM in DMSO|H2O : ≥ 100 mg/mL |
Target |
Bradykinin Receptor; Endogenous Metabolite; Ser/Thr Protease |
Manufacturers Target |
Bradykinin Receptor; Endogenous Metabolite; Ser/Thr Protease |
Isoform |
Bradykinin B2 Receptor (B2R); Human Endogenous Metabolite |
Manufacturers Pathway |
GPCR/G Protein; Metabolic Enzyme/Protease |
Manufacturers Product type |
Peptides |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.