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Motixafortide

Motixafortide

Item no.	HY-P0171-5mg
Manufacturer	MedChem Express
CASRN	664334-36-5
Amount	5 mg
Quantity options	100 mg 10mM*1 mL 10 mg 1mg 25 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules By Organ Heart & Blood Cancer Lymphatic System Cancer
Type	Inhibitors
Specific against	other
Purity	99.88
Formula	C97H144FN33O19S2
Citations	[1]Peled A, et al. The high-affinity CXCR4 antagonist BKT140 is safe and induces a robust mobilization of human CD34+ cellsin patients with multiple myeloma. Clin Cancer Res. 2014 Jan 15;20(2):469-79.<br>[2]Beider K, et al. CXCR4 antagonist 4F-benzoyl-TN14003 inhibits leukemia and multiple myeloma tumor growth. Exp Hematol. 2011 Mar;39(3):282-92.
Smiles	O=C1[C@@]2([H])N(CCC2)C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](N1)CC3=CC=C(C=C3)O)=O)CCCNC(N)=N)=O)CCCNC(N)=O)=O)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC(C4=CC=C(C=C4)F)=O)=O)=O)CC5=CC6=C(C=CC=C6)C=C5)=O)=O)CC7=CC=C(C=C7)O)=O)CCCNC(N)=O)=O)CCCCN)=O)CCCCN)=O
ECLASS 5.1	30220300
ECLASS 6.1	30220300
ECLASS 8.0	32160605
ECLASS 9.0	32160605
ECLASS 10.0.1	32160490
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	BKT140 (4-fluorobenzoyl); BL-8040; TF14016
Available
Product Description	Motixafortide (BKT140 4-fluorobenzoyl) is a novel CXCR4 antagonist with an IC50 vakue of ～1 nM.
StorageTemperature	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	2159.52
Clinical_Information	Launched
Manufacturers Research Area	Cancer; Endocrinology
Solubility	DMSO : ≥ 100 mg/mL\|H2O : 50 mg/mL (ultrasonic)
Manufacturers Target	CXCR
Isoform	CXCR4
Pathway	GPCR/G Protein; Immunology/Inflammation

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-P0171-5mg-safety-datasheet.pdf