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3'-Demethylnobiletin

3'-Demethylnobiletin

Item no.	HY-N4127-1mg
Manufacturer	MedChem Express
CASRN	112448-39-2
Amount	1 mg
Quantity options	10 mg 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.98
Formula	C20H20O8
Citations	[1]Murakami A, et al. In vitro absorption and metabolism of nobiletin, a chemopreventive polymethoxyflavonoid in citrus fruits. Biosci Biotechnol Biochem. 2001 Jan;65(1):194-7.<br/>[2]Sp N, et al. Nobiletin Inhibits Angiogenesis by Regulating Src/FAK/STAT3-Mediated Signaling through PXN in ER<sup>+</sup> Breast Cancer Cells. Int J Mol Sci. 2017 Apr 30;18(5). pii: E935.
Smiles	O=C1C=C(C2=CC=C(OC)C(O)=C2)OC3=C(OC)C(OC)=C(OC)C(OC)=C13
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	112448-39-2
Available
Product Description	3'-Demethylnobiletin, a derivative of Nobiletin, is a polymethoxyflavonoid in citrus fruits[1]. Nobiletin exhibits anticancer activity and inhibits tumor angiogenesis by regulating Src, FAK, and STAT3 signaling[2].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	388.37
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	Src; STAT
Manufacturers Target	Src; STAT
Manufacturers Pathway	JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Manufacturers Product type	Natural Products

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