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Combretastatin A4

Combretastatin A4

Item no.	HY-N2146-25mg
Manufacturer	MedChem Express
CASRN	117048-59-6
Amount	25 mg
Quantity options	10mM/1mL 10 mg 25 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Adhesion Molecules Inhibitors & Compound Libraries Small Molecules By Organ Head & Neck Cancer Astrocyte Markers
Type	Inhibitors
Specific against	other
Purity	99.76
Formula	C18H20O5
Citations	[1]Yao N, et al. Combretastatin A4 phosphate treatment induces vasculogenic mimicry formation of W256 breast carcinoma tumor in vitro and in vivo. Tumour Biol. 2015 Nov;36(11):8499-510<br>[2]Tochinai R, et al. Combretastatin A4 disodium phosphate-induced myocardial injury. J Toxicol Pathol. 2016 Jul;29(3):163-71.<br>[3]Signoretto E, et al. Stimulation of Eryptosis by Combretastatin A4 Phosphate Disodium (CA4P). Cell Physiol Biochem. 2016;38(3):969-8<br>[4]Zhu J, et al. Co-Encapsulation of Combretastatin-A4 Phosphate and Doxorubicin in Polymersomes for Synergistic Therapy of Nasopharyngeal Epidermal Carcinoma. J Biomed Nanotechnol. 2015 Jun;11(6):997-1006.
Smiles	OC1=CC(/C=C\C2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	CRC 87-09
Available
Product Description	Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	316.35
Clinical_Information	Phase 2
Manufacturers Research Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturers Target	Microtubule/Tubulin
Pathway	Cell Cycle/DNA Damage; Cytoskeleton

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-N2146-25mg-safety-datasheet.pdf