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Chebulinic acid

Chebulinic acid

Item no.	HY-N2033-2mg
Manufacturer	MedChem Express
CASRN	18942-26-2
Amount	2mg
Quantity options	10mM/1mL 10 mg 1 mg 25mg 2mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.42
Citations	[1]Patel K et al. Identification of chebulinic acid as potent natural inhibitor of M. tuberculosis DNA gyrase and molecular insights into its binding mode of action. Comput Biol Chem. 2015 Dec;59 Pt A:37-47.<br/>[2]Sivasankar S et al. Aqueous and alcoholic extracts of Triphala and their active compounds chebulagic acid and chebulinic acidprevented epithelial to mesenchymal transition in retinal pigment epithelial cells, by inhibiting SMAD-3 phosphorylation. PLoS One. 2015 Mar 20<br/>[3]Mishra V et al. Anti-secretory and cyto-protective effects of chebulinic acid isolated from the fruits of Terminalia chebula on gastric ulcers. Phytomedicine. 2013 Apr 15;20(6):506-11.
Smiles	OC(C[C@H](C(O[C@@]([C@H](O[C@H]1OC(C2=CC(O)=C(O)C(O)=C2)=O)COC(C3=CC(O)=C(O)C(O)=C3)=O)([H])[C@@](OC(C4=CC(O)=C(O)C(O)=C4)=O)([H])[C@@]1([H])OC5=O)=O)[C@@]([C@H]6O)([H])C(C5=CC(O)=C7O)=C7OC6=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Chebulinic acid is a potent natural inhibitor of M. tuberculosis DNA gyrase, also can inhibit SMAD-3 phosphorylation, inhibit H+ K+-ATPase activity.
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	956.68
Clinical Information	No Development Reported
Manufacturers Research Area	Infection
Solubility	DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Target	DNA/RNA Synthesis; Proton Pump; TGF-beta/Smad
Manufacturers Target	DNA/RNA Synthesis; Proton Pump; TGF-beta/Smad
Manufacturers Pathway	Cell Cycle/DNA Damage; Membrane Transporter/Ion Channel; Stem Cell/Wnt; TGF-beta/Smad
Manufacturers Product type	Natural Products

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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