Comparison

Dihydrocoumarin European Partner

Item no. HY-N1926-10mM
Manufacturer MedChem Express
CASRN 119-84-6
Amount 10mM/1mL
Quantity options 100 mg 10 g 10mM/1mL 25 g
Category
Type Inhibitors
Specific against other
Purity 99.81
Formula C9H8O2
Citations [1]Olaharski AJ, et al. The flavoring agent Dihydrocoumarin reverses epigenetic silencing and inhibits sirtuindeacetylases. PLoS Genet. 2005 Dec;1(6):e77.
Smiles O=C1CCC2=CC=CC=C2O1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias Hydrocoumarin; Chroman-2-one
Available
Product Description
Dihydrocoumarin is a compound found in Melilotus officinalis. Dihydrocoumarin is a yeast Sir2p inhibitor. Dihydrocoumarin also inhibits human SIRT1 and SIRT2 with IC50s of 208 μM and 295 μM, respectively[1].
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Manufacturers Applications
Cancer-programmed cell death
MolecularWeight
148.16
Clinical Information
No Development Reported
Manufacturers Research Area
Cancer
Solubility
DMSO : 100 mg/mL (ultrasonic)
Target
Sirtuin
Manufacturers Target
Sirtuin
Isoform
SIRT1; SIRT2
Manufacturers Pathway
Cell Cycle/DNA Damage; Epigenetics
Manufacturers Product type
Natural Products

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10mM/1mL
Available: In stock
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