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Dencichine

Dencichine

Item no.	HY-N1477-10mg
Manufacturer	MedChem Express
CASRN	5302-45-4
Amount	10 mg
Quantity options	10mM/1mL 10 mg 25 mg 5 mg
Category	Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.93
Citations	[1]Eslavath RK, et al. β-N-oxalyl-L-α, β- diaminopropionic acid induces HRE expression by inhibiting HIF-prolyl hydroxylase-2 in normoxic conditions. Eur J Pharmacol. 2016 Nov 15;791:405-411.<br/>[2]Jie L, et al. Dencichine ameliorates kidney injury in induced type II diabetic nephropathy via the TGF-β/Smad signalling pathway. Eur J Pharmacol. 2017 Oct 5;812:196-205.
Smiles	N[C@@H](CNC(C(O)=O)=O)C(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Dencichin; ODAP
Available
Product Description	Dencichin is a non-protein amino acid originally extracted from Panax notoginseng, and can inhibit HIF-prolyl hydroxylase-2 (PHD-2) activity.
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	176.13
Clinical Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	0.1 M HCL : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)\|DMSO : 5 mg/mL (ultrasonic)\|H2O : 5 mg/mL (ultrasonic)
Target	HIF/HIF Prolyl-Hydroxylase
Manufacturers Target	HIF/HIF Prolyl-Hydroxylase
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Natural Products

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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