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Citric acid

Citric acid

Item no.	HY-N1428-10mM
Manufacturer	MedChem Express
CASRN	77-92-9
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 500g
Category	Food Safety Neuroscience Metabolism Diabetes Glucose Homeostasis Molecular Targets for Neuroscience Neural Development Inhibitors & Compound Libraries Small Molecules Acid Determination
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C6H8O7
Citations	Food Chem. 2022: 134807.<br>New J Chem. 03 Aug 2022.<br>Insect Biochem Mol Biol. 2023 May 12;103958.<br>[1]Chen X, et al. Study on injury effect of food additive citric acid on liver tissue in mice. Cytotechnology. 2014 Mar;66(2):275-82.<br>[2]Chen X, Lv Q, Liu Y, Deng W. Effects of the food additive, citric acid, on kidney cells of mice. Biotech Histochem. 2015 Jan;90(1):38-44. <br>[3]Ying TH, et al. Citric acid induces cell-cycle arrest and apoptosis of human immortalized keratinocyte cell line (HaCaT) via caspase- and mitochondrial-dependent signaling pathways. Anticancer Res. 2013 Oct;33(10):4411-20.
Smiles	OC(CC(CC(O)=O)(C(O)=O)O)=O
ECLASS 5.1	30220300
ECLASS 6.1	30220300
ECLASS 8.0	32160605
ECLASS 9.0	32160605
ECLASS 10.0.1	32160490
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	77-92-9
Available
Product Description	Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice[1][2][3].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	192.12
Clinical_Information	Launched
Manufacturers Research Area	Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)\|H2O : 100 mg/mL (ultrasonic)
Manufacturers Target	Antibiotic; Apoptosis; Endogenous Metabolite
Isoform	Human Endogenous Metabolite
Pathway	Anti-infection; Apoptosis; Metabolic Enzyme/Protease

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-N1428-10mM-safety-datasheet.pdf