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Citric acid

Citric acid

Item no.	HY-N1428-10mM
Manufacturer	MedChem Express
CASRN	77-92-9
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 500 g
Category	Food Safety Neuroscience Metabolism Diabetes Glucose Homeostasis Molecular Targets for Neuroscience Neural Development Inhibitors & Compound Libraries Small Molecules Acid Determination
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C6H8O7
Citations	[1]Chen X, et al. Study on injury effect of food additive citric acid on liver tissue in mice. Cytotechnology. 2014 Mar;66(2):275-82. [2]Chen X, Lv Q, Liu Y, Deng W. Effects of the food additive, citric acid, on kidney cells of mice. Biotech Histochem. 2015 Jan;90(1):38-44. [3]Ying TH, et al. Citric acid induces cell-cycle arrest and apoptosis of human immortalized keratinocyte cell line (HaCaT) via caspase- and mitochondrial-dependent signaling pathways. Anticancer Res. 2013 Oct;33(10):4411-20. Food Chem. 2022: 134807. New J Chem. 03 Aug 2022. Bioengineered. 2021 Dec;12(2):11610-11621. Biol Trace Elem Res. 2023 May 8. Biomed Pharmacother. 2023 Aug 18;166:115333. Drug Des Devel Ther. 2024 Feb 1:18:259-275. Front Mol Biosci. 22 July 2022. Int J Biol Sci. 2024 Aug 6;20(11):4222-4237. Oxid Med Cell Longev. 2022 Apr 25;2022:3846217. Research Square Preprint. 2021 Jul. Carbohydr Polym. 2024 Dec 15:346:122645. Exp Cell Res. 2020 Aug 1;393(1):112054. Heliyon. 2024 Jan 17. J Ethnopharmacol. 2024 Jan 12:117759. J Mol Med (Berl). 2019 Aug;97(8):1183-1193. J Nanobiotechnology. 2023 Oct 19;21(1):383. Nat Commun. 2024 Sep 10;15(1):7923. Nature. 2023 Jun;618(7964):374-382. Phytother Res. 2024 Mar 25. SSRN. 2024 Mar 20. Theranostics. 2020 Jul 25;10(21):9477-9494. Insect Biochem Mol Biol. 2023 May 12;103958. J Virol. 2023 Jun 22;e0051223. Regen Biomater. 2024 Aug 22:11:rbae098.
Smiles	OC(CC(CC(O)=O)(C(O)=O)O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	77-92-9
Shipping condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Antibiotic; Apoptosis; Endogenous Metabolite
Shipping Temperature	Room Temperature
Storage Conditions	Store at room temperature 3 years
Molecular Weight	192.123
Product Description	Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice[1][2][3].
Manufacturer - Research Area	Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)\|H2O : 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Apoptosis; Metabolic Enzyme/Protease
Isoform	Human Endogenous Metabolite
Clinical information	Launched

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HY-N1428-10mM-safety-datasheet.pdf