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Micheliolide

Micheliolide

Item no.	HY-N0847-10mM
Manufacturer	MedChem Express
CASRN	68370-47-8
Amount	10mM/1mL
Quantity options	10mM/1mL 10 mg 1 mg 5 mg
Category	Oncology Neuroscience Neuroinflammation Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer
Type	Inhibitors
Specific against	other
Purity	99.84
Formula	C15H20O3
Citations	[1]Jia QQ, et al. Sesquiterpene lactones and their derivatives inhibit high glucose-induced NF-κB activation and MCP-1 and TGF-β1 expression in rat mesangial cells. Molecules. 2013 Oct 21;18(10):13061-77.
Smiles	O=C(O[C@@]1([H])[C@@]2([H])CCC(C)=C3CC[C@@](C)(O)[C@@]31[H])C2=C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Micheliolide can attenuate high glucose-stimulated NF-κB activation, IκBα degradation, and the expression of MCP-1, TGF-β1, and FN in mouse mesangial cells.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
MolecularWeight	248.32
Clinical_Information	No Development Reported
Manufacturers Research Area	Others
Solubility	DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	NF-κB
Pathway	NF-κB

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HY-N0847-10mM-safety-datasheet.pdf