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Bevirimat

Bevirimat

Item no.	HY-N0842-5mg
Manufacturer	MedChem Express
CASRN	174022-42-5
Amount	5 mg
Quantity options	10mM/1mL 10 mg 1 mg 25 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.80
Formula	C36H56O6
Citations	[1]Smith PF, et al. Phase I and II study of the safety, virologic effect, and pharmacokinetics/pharmacodynamics of single-dose 3-o-(3',3'-dimethylsuccinyl)betulinic acid (bevirimat) against human immunodeficiency virus infection. Antimicrob Agents Chemother. 2007 Oct;51(10):3574-81.<br/>[2]Salzwedel K, et al. Maturation inhibitors: a new therapeutic class targets the virus structure. AIDS Rev. 2007 Jul-Sep;9(3):162-72.<br/>[3]Martin DE, et al. Bevirimat: a novel maturation inhibitor for the treatment of HIV-1 infection. Antivir Chem Chemother. 2008;19(3):107-13.
Smiles	OC([C@]1(CC[C@H]2C(C)=C)[C@@]2([H])[C@](CC[C@@]3([H])[C@]4(CC[C@]5([H])[C@@]3(CC[C@H](OC(CC(C)(C)C(O)=O)=O)C5(C)C)C)C)([H])[C@@]4(C)CC1)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	PA-457; MPC-4326; YK FH312
Available
Product Description	Bevirimat (PA-457; MPC-4326; YK FH312) is an anti-HIV agent derived from a betulinic acid-like compound; is believed to inhibit HIV by a novel mechanism, so-called maturation inhibition.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-anti-virus
MolecularWeight	584.83
Clinical Information	Phase 2
Manufacturers Research Area	Infection
Solubility	DMSO : ≥ 50 mg/mL
Target	HIV
Manufacturers Target	HIV
Manufacturers Pathway	Anti-infection
Manufacturers Product type	Natural Products

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HY-N0842-5mg-safety-datasheet.pdf