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Leonurine (hydrochloride)

Leonurine (hydrochloride)

Item no.	HY-N0741A-10mM
Manufacturer	MedChem Express
CASRN	24735-18-0
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Oncology Food Safety Hormones Neuroscience Neuroinflammation Neural Signaling Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer Lymphatic System Cancer Bone Cancer
Type	Inhibitors
Specific against	other
Purity	99.43
Formula	C14H22ClN3O5
Citations	[1]Jiang T, et al. Leonurine Prevents Atherosclerosis Via Promoting the Expression of ABCA1 and ABCG1 in a Pparγ/Lxrα Signaling Pathway-Dependent Manner. Cell Physiol Biochem. 2017;43(4):1703-1717. [2]Zhang L, et al. Novel hepatoprotective role of Leonurine hydrochloride against experimental non-alcoholic steatohepatitis mediated via AMPK/SREBP1 signaling pathway. Biomed Pharmacother. 2018 Dec 7;110:571-581. [3]Hu ZC, et al. Inhibition of PI3K/Akt/NF-κB signaling with leonurine for ameliorating the progression of osteoarthritis: In vitro and in vivo studies. J Cell Physiol. 2018 Nov 11.
Smiles	O=C(OCCCCNC(N)=N)C1=CC(OC)=C(O)C(OC)=C1.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	SCM-198 hydrochloride
Shipping condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Autophagy; Toll-like Receptor (TLR)
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	347.79
Product Description	Leonurine hydrochloride is an alkaloid isolated from Leonurus artemisia, with anti-oxidative and anti-inflammatory.
Manufacturer - Research Area	Inflammation/Immunology; Cancer
Solubility	DMSO : ≥ 31 mg/mL\|H2O : 5 mg/mL (ultrasonic)
Manufacturer - Pathway	Autophagy; Immunology/Inflammation
Clinical information	No Development Reported

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HY-N0741A-10mM-safety-datasheet.pdf