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L-Leucine

L-Leucine

Item no.	HY-N0486-10mM
Manufacturer	MedChem Express
CASRN	61-90-5
Amount	10 mMx1 mL
Quantity options	100 mg 10 mMx1 mL 250 mg 500 mg
Category	Food Safety Inhibitors & Compound Libraries Small Molecules Amino Acid Analysis
Type	Inhibitors
Specific against	other
Purity	99.79
Citations	[1]Baoshan Xu, et al. Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome. PLoS Genet. 2013;9(10):e1003857. [2]Bruckbauer A, et al. Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice. Nutr Metab (Lond). 2012 Aug 22;9(1):77. [3]Rachdi L, et al. L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway. Diabetes. 2012 Feb;61(2):409-17.
Smiles	N[C@@H](CC(C)C)C(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Leucine
Shipping condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Metabolism-sugar/lipid metabolism
Manufacturer - Targets	Endogenous Metabolite; mTOR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	131.17
Product Description	L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
Manufacturer - Research Area	Metabolic Disease; Cancer
Solubility	H2O : 8.33 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease; PI3K/Akt/mTOR
Isoform	Human Endogenous Metabolite; Microbial Metabolite; mTORC1
Clinical information	Launched

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-N0486-10mM-safety-datasheet.pdf