Item no. |
HY-N0455-1g |
Manufacturer |
MedChem Express
|
CASRN |
74-79-3 |
Amount |
1 g |
Quantity options |
100 g
10 mM/1 mL
1 g
500 g
500 mg
5 g
|
Category |
|
Type |
Inhibitors |
Specific against |
other |
Purity |
99.89 |
Formula |
C6H14N4O2 |
Citations |
[1]Tapiero H, et al. I. Arginine. Biomed Pharmacother. 2002 Nov;56(9):439-45. [2]Bakker J, et al. Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002). Crit Care Med. 2004 Jan;32(1):1-12. [3]Yamada M, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr;20(4):709-17. [4]Mizunuma T, et al. Effects of injecting excess arginine on rat pancreas. J Nutr. 1984 Mar;114(3):467-71. [5]Siriviriyakul P, et al. Effects of curcumin on oxidative stress, inflammation and apoptosis in L-arginine induced acute pancreatitis in mice. Heliyon. 2019 Aug 27;5(8):e02222. |
Smiles |
N[C@@H](CCCNC(N)=N)C(O)=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
L-Arginine |
Shipping condition |
Room temperature |
Available |
|
Manufacturer - Type |
Natural Products |
Manufacturer - Applications |
Metabolism-protein/nucleotide metabolism |
Manufacturer - Targets |
Endogenous Metabolite; NO Synthase |
Shipping Temperature |
Room Temperature |
Storage Conditions |
Store at room temperature 3 years |
Molecular Weight |
174.20 |
Product Description |
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis[1][2][3][4][5]. |
Manufacturer - Research Area |
Cardiovascular Disease; Cancer |
Solubility |
H2O : 50 mg/mL (ultrasonic) |
Manufacturer - Pathway |
Immunology/Inflammation; Metabolic Enzyme/Protease |
Isoform |
eNOS; Human Endogenous Metabolite; Microbial Metabolite |
Clinical information |
Launched |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.