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L-Arginine

L-Arginine

Item no.	HY-N0455-1g
Manufacturer	MedChem Express
CASRN	74-79-3
Amount	1 g
Quantity options	100g 10mM/1mL 1 g 500g 500 mg 5 g
Category	Food Safety Cardiovascular Research Heart Failure Hypertension Inhibitors & Compound Libraries Small Molecules Amino Acid Analysis
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C6H14N4O2
Citations	[1]Tapiero H, et al. I. Arginine. Biomed Pharmacother. 2002 Nov;56(9):439-45.<br>[2]Bakker J, et al. Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002). Crit Care Med. 2004 Jan;32(1):1-12.<br>[3]Yamada M, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr;20(4):709-17.<br>[4]Mizunuma T, et al. Effects of injecting excess arginine on rat pancreas. J Nutr. 1984 Mar;114(3):467-71.<br>[5]Siriviriyakul P, et al. Effects of curcumin on oxidative stress, inflammation and apoptosis in L-arginine induced acute pancreatitis in mice. Heliyon. 2019 Aug 27;5(8):e02222.
Smiles	N[C@@H](CCCNC(N)=N)C(O)=O
ECLASS 5.1	30220300
ECLASS 6.1	30220300
ECLASS 8.0	32160605
ECLASS 9.0	32160605
ECLASS 10.0.1	32160490
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	L-Arginine
Available
Product Description	L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis[1][2][3][4][5].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
MolecularWeight	174.20
Clinical_Information	Launched
Manufacturers Research Area	Cardiovascular Disease; Cancer
Solubility	H2O : 50 mg/mL (ultrasonic)
Manufacturers Target	Endogenous Metabolite; NO Synthase
Isoform	eNOS; Human Endogenous Metabolite; Microbial Metabolite
Pathway	Immunology/Inflammation; Metabolic Enzyme/Protease

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-N0455-1g-safety-datasheet.pdf