Item no. |
HY-N0148A-10mM |
Manufacturer |
MedChem Express
|
CASRN |
207671-50-9 |
Amount |
10mM*1 mL |
Quantity options |
10g
10mM*1 mL
500 mg
5g
|
Category |
|
Type |
Inhibitors |
Specific against |
other |
Purity |
98.99 |
Citations |
[1]Ghorbani A. Mechanisms of antidiabetic effects of flavonoid rutin. Biomed Pharmacother. 2017;96:305-312.<br>[2]Habtemariam S. Rutin as a Natural Therapy for Alzheimer's Disease: Insights into its Mechanisms of Action. Curr Med Chem. 2016;23(9):860-873.<br>[3]Xu PX, et al. Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation. Behav Brain Res. 2014;264:173-180.<br>[4]Abdel-Aleem GA, et al. Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signalling. Arch Physiol Biochem. 2018;124(4):367-377. |
Smiles |
O=C1C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]3[C@@H]([C@@H]([C@H]([C@H](C)O3)O)O)O)O2)O)O)O)=C(C4=CC=C(O)C(O)=C4)OC5=CC(O)=CC(O)=C15.O.[36/5] |
ECLASS 5.1 |
30220300 |
ECLASS 6.1 |
30220300 |
ECLASS 8.0 |
32160605 |
ECLASS 9.0 |
32160605 |
ECLASS 10.0.1 |
32160490 |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
Rutoside (hydrate); Quercetin 3-O-rutinoside (hydrate) |
Available |
|
Product Description |
Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress[1][2][3]. |
StorageTemperature |
4°C (Powder, protect from light) |
Shipping |
Room Temperature |
Manufacturers Applications |
Neuroscience-Neuromodulation |
MolecularWeight |
713.04 |
Clinical_Information |
Launched |
Manufacturers Research Area |
Cancer; Neurological Disease |
Solubility |
DMSO : 50 mg/mL (ultrasonic) |
Manufacturers Target |
Amyloid-β; Apoptosis; Autophagy; Endogenous Metabolite |
Pathway |
Apoptosis; Autophagy; Metabolic Enzyme/Protease; Neuronal Signaling |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.