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Bergenin

Bergenin

Item no.	HY-N0017-10mM
Manufacturer	MedChem Express
CASRN	477-90-7
Amount	10mM/1mL
Quantity options	10mM/1mL 10 mg 2 mg 50 mg 5 mg
Category	Metabolism Diabetes Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.21
Formula	C14H16O9
Citations	[1]Shi X, et al. Anticancer activity of bergenin against cervical cancer cells involves apoptosis, cell cycle arrest, inhibition of cell migration and the STAT3 signalling pathway. Exp Ther Med. 2019 May;17(5):3525-3529.<br/>[2]Yun J, et al. Bergenin decreases the morphine-induced physical dependence via antioxidative activity in mice. Arch Pharm Res. 2015 Jun;38(6):1248-54.<br/>[3]de Oliveira CM, et al. Antinociceptive properties of bergenin. J Nat Prod. 2011 Oct 28;74(10):2062-8.
Smiles	OC1=C(OC)C(O)=C([C@@]2([H])[C@@](OC3=O)([H])[C@@H](O)[C@H](O)[C@@H](CO)O2)C3=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Cuscutin
Available
Product Description	Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	328.27
Clinical Information	Launched
Manufacturers Research Area	Cancer; Infection; Inflammation/Immunology
Solubility	DMSO : 103.3 mg/mL (ultrasonic; warming)
Target	Apoptosis; Autophagy; Bacterial; Fungal; NF-κB; Virus Protease
Manufacturers Target	Apoptosis; Autophagy; Bacterial; Fungal; NF-κB; Virus Protease
Manufacturers Pathway	Anti-infection; Apoptosis; Autophagy; NF-κB
Manufacturers Product type	Natural Products

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-N0017-10mM-safety-datasheet.pdf