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Citalopram (hydrobromide)

Citalopram (hydrobromide)

Item no.	HY-B1287-50mg
Manufacturer	MedChem Express
CASRN	59729-32-7
Amount	50 mg
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.93
Formula	C20H22BrFN2O
Citations	Eur J Pharmacol. 2018 Sep 27;841:57-66.<br>J Clin Psychopharmacol. 2021 Jun 11.<br>Neurochem Int. 2019 Dec;131:104552.<br>Pharmacol Res Perspect. 2020 Apr;8(2):e00575.<br>Research Square Preprint. 2021 Feb.<br>Comput Struct Biotechnol J. 2023 Jul 7, 21, 3490-3502.<br>[1]J Hyttel. Citalopram--pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity. Prog Neuropsychopharmacol Biol Psychiatry. 1982;6(3):277-95.<br>[2]Laurent Sakka, et al. Assessment of citalopram and escitalopram on neuroblastoma cell lines. Cell toxicity and gene modulation. Oncotarget. 2017 Jun 27;8(26):42789-42807.<br>[3]F Pollier, et al. Serotonin reuptake inhibition by citalopram in rat strains differing for their emotionality. Neuropsychopharmacology. 2000 Jan;22(1):64-76.
Smiles	N#CC1=CC2=C(C(C3=CC=C(F)C=C3)(CCCN(C)C)OC2)C=C1.[H]Br
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	(±)-Citalopram hydrobromide; Lu 10-171
Available
Product Description	Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI). Citalopram hydrobromide inhibits 5-HT uptake into synaptosomes with an IC50 of 1.8 nM. Citalopram hydrobromideinhibits the 5-HT uptake in rabbit blood platelets with an IC50 of 14 nM. Antidepressant effect[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	405.30
Clinical_Information	Launched
Manufacturers Research Area	Neurological Disease; Cancer
Solubility	DMSO : ≥ 38 mg/mL\|H2O : 10 mg/mL (ultrasonic)
Manufacturers Target	Autophagy; Serotonin Transporter
Pathway	Autophagy; Neuronal Signaling

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HY-B1287-50mg-safety-datasheet.pdf