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Ingenol Mebutate

Ingenol Mebutate

Manufacturer	MedChem Express
Category	Oncology Metabolism Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer
Type	Inhibitors
Specific against	other
Amount	10 mg
Quantity options	10mM/1mL 10 mg 1 mg 5 mg
Item no.	HY-B0719-10mg
Targets	PKC
CASRN	75567-37-2
eClass 6.1	30220300
eClass 9.0	32160605
Available
Alias	Ingenol 3-angelate; PEP005
Purity	99.65
Product Description	Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	430.53
Clinical_Information	Launched
Manufacturers Research Area	Cancer; Inflammation/Immunology
Solubility	DMSO : ≥ 100 mg/mL
Manufacturers Target	PKC
Isoform	PKCα; PKCβ; PKCγ; PKCδ; PKCε
Pathway	Epigenetics; TGF-beta/Smad

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-B0719-10mg-safety-datasheet.pdf