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Lacidipine

Lacidipine

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Clone	N/A
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 10 mg 200 mg 50 mg 5 mg
Item no.	HY-B0347-10mM
Targets	Calcium Channel; Reactive Oxygen Species; Apoptosis
CASRN	103890-78-4
eClass 6.1	30220300
eClass 9.0	32160605
Available
Alias	103890-78-4
Purity	99.79
Product Description	Lacidipine is an orally active and highly selective L-type calcium channel blocker that acts on smooth muscle calcium channels, primarily dilates peripheral arteries, reduces peripheral resistance, and has long-lasting anti-hypertensive activity. Lacidipine protects HKCs from apoptosis induced by ATP depletion and recovery by modulating the caspase-3 pathway. Lacidipine can be used in studies of hypertension, atherosclerosis and acute kidney injury (AKI)[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	455.54
Clinical_Information	Launched
Manufacturers Research Area	Cardiovascular Disease
Solubility	DMSO : ≥ 50 mg/mL
Manufacturers Target	Apoptosis; Calcium Channel; Caspase; Reactive Oxygen Species
Isoform	L-type calcium channel
Pathway	Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-B0347-10mM-safety-datasheet.pdf