Item no. |
HY-B0307-10mM |
Manufacturer |
MedChem Express
|
CASRN |
54-42-2 |
Amount |
10mM/1mL |
Quantity options |
10g
10mM/1mL
1 g
500 mg
5 g
|
Category |
|
Type |
Inhibitors |
Clone |
N/A |
Specific against |
other |
Purity |
99.95 |
Formula |
C9H11IN2O5 |
Citations |
[1]David J Maggs, et al. In vitro efficacy of ganciclovir, cidofovir, penciclovir, foscarnet, idoxuridine, and acyclovir against feline herpesvirus type-1. Am J Vet Res. 2004 Apr;65(4):399-403.<br/>[2]D E Griswold, et al. Stimulation of hemolysin plaque-forming cells by idoxuridine. Cancer Res. 1975 Jan;35(1):88-92.<br/>[3]Mark N Prichard, et al. Orthopoxvirus targets for the development of antiviral therapies. Curr Drug Targets Infect Disord |
Smiles |
O=C(N1)N([C@H]2C[C@H](O)[C@@H](CO)O2)C=C(I)C1=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
5-Iodo-2′-deoxyuridine; 5-IUdR; IdUrd |
Available |
|
Product Description |
Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM[1]. Idoxuridine shows anti-orthopoxvirus activity. |
StorageTemperature |
-20°C, 3 years; 4°C, 2 years (Powder) |
Shipping |
Room Temperature |
Manufacturers Applications |
COVID-19-anti-virus |
MolecularWeight |
354.10 |
Clinical Information |
Launched |
Manufacturers Research Area |
Infection; Cancer |
Solubility |
DMSO : 125 mg/mL (ultrasonic) |
Target |
Orthopoxvirus; Phosphatase |
Manufacturers Target |
Orthopoxvirus; Phosphatase |
Isoform |
HSV-1 |
Manufacturers Pathway |
Anti-infection; Metabolic Enzyme/Protease |
Manufacturers Product type |
Reference compound |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.