« Back
Home /
Imiquimod (hydrochloride)

Imiquimod (hydrochloride)

Item no.	HY-B0180A-500mg
Manufacturer	MedChem Express
CASRN	99011-78-6
Amount	500 mg
Quantity options	100 mg 10mM/1mL 200 mg 500 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.77
Formula	C14H17ClN4
Citations	bioRxiv. 2024 Apr 20.<br/>Int J Pharm. 2023 Nov 7:648:123583.<br/>J Nanobiotechnology. 2023 Feb 10;21(1):50.<br/>Nat Commun. 2022 Jul 22;13(1):4255.<br/>Nucleic Acids Res. 2021 Jan 8;49(D1):D1113-D1121.<br/>protocols.io. 2024 Apr 13.<br/>Virulence. 2023 Dec;14(1):2223394.<br/>ACS Appl Bio Mater. 2019, 2, 874-883.<br/>Am J Respir Cell Mol Biol. 2022 Oct 13.<br/>Biochem Biophys Res Commun. 2024 Feb 15, 149661.<br/>Biomaterials. 2021, 120724.<br/>Biomaterials. 2022 Feb 14;282:121411.<br/>Cell Commun Signal. 2023 Aug 18;21(1):215.<br/>Cell Rep. 2021 Feb 2;34(5):108724.<br/>Diam Relat Mater. 2023 May 26, 110058.<br/>Drug Deliv. 2023 Dec;30(1):2183814.<br/>EMBO Rep. 2022 Feb 3;23(2):e53499.<br/>FEBS Lett. 2021 Aug 13.<br/>J Agric Food Chem. 2024 Jan 3.<br/>J Cell Mol Med. 2024 Apr;28(8):e18356.<br/>J Control Release. 2023 Aug 12;361:443-454.<br/>J Ethnopharmacol. 2024 Jan 2:117711.<br/>J Invest Dermatol. 2021 Oct 20;S0022-202X(21)02369-1.<br/>J Nanobiotechnology. 2022 May 14;20(1):228.<br/>MedComm. 04 March 2022.<br/>Nat Commun. 2016 May 25;7:11724. <br/>Nucleic Acids Res. 2021 Jan 8;49(D1):D1113-D1121.<br/>Oxid Med Cell Longev. 12 Oct 2022.<br/>Research Square Preprint. 2021 Oct.<br/>Research Square Preprint. 2023 Nov 17.<br/>Research Square Print. 2023 Feb 1.<br/>Sci Rep. 2024 Mar 4;14(1):5237.<br/>Theranostics. 2023 Apr 9;13(7):2226-2240.<br/>Nucleic Acids Res. 2021 Jan 8;49(D1):D1113-D1121.<br/>Pharmacol Res. 2023 Nov 24:198:107016.<br/>[1]Athina Angelopoulou, et al. Imiquimod - A toll like receptor 7 agonist - Is an ideal option for management of COVID 19. Environ Res. 2020 Sep; 188: 109858.<br/>[2]Michael P Schön, et al. The small antitumoral immune response modifier imiquimod interacts with adenosine receptor signaling in a TLR7- and TLR8-independent fashion. J Invest Dermatol. 2006 Jun;126(6):1338-47.<br/>[3]Aditya K Gupta, et al. Imiquimod: a review. J Cutan Med Surg. Nov-Dec 2002;6(6):554-60.<br/>[4]Yuji Kan, et al. Imiquimod suppresses propagation of herpes simplex virus 1 by upregulation of cystatin A via the adenosine receptor A1 pathway. J Virol. 2012 Oct;86(19):10338-46.
Smiles	NC1=NC2=CC=CC=C2C3=C1N=CN3CC(C)C.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	R 837 (hydrochloride)
Available
Product Description	Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19[1][2].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-anti-virus
MolecularWeight	276.76
Clinical Information	Launched
Manufacturers Research Area	Cancer; Infection; Inflammation/Immunology
Solubility	DMSO : 8 mg/mL (ultrasonic; warming; heat to 50°C)\|Ethanol : 3.85 mg/mL (ultrasonic)\|H2O : 4.8 mg/mL (ultrasonic)\|Methanol : 24 mg/mL (ultrasonic)
Target	Autophagy; HSV; SARS-CoV; Toll-like Receptor (TLR)
Manufacturers Target	Autophagy; HSV; SARS-CoV; Toll-like Receptor (TLR)
Isoform	HSV-1; TLR7
Manufacturers Pathway	Anti-infection; Autophagy; Immunology/Inflammation
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-B0180A-500mg-safety-datasheet.pdf