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Lafutidine

Lafutidine

Item no.	HY-B0160-10mg
Manufacturer	MedChem Express
CASRN	118288-08-7
Amount	10 mg
Quantity options	100 mg 10 mM x 1 mL 10 mg 25 mg 50 mg
Category	Oncology Food Safety Histamines Inhibitors & Compound Libraries Small Molecules By Organ Thyroid Cancer
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.95
Citations	[1]Motoko Nakano, et al. Possible involvement of host defense mechanism in the suppression of rat acute reflux esophagitis by the particular histamine H2 receptor antagonist lafutidine. Pharmacology. 2012;90(3-4):205-11. [2]Tetsuhiro Sugiyama, et al. Lafutidine facilitates calcitonin gene-related peptide (CGRP) nerve-mediated vasodilation via vanilloid-1 receptors in rat mesenteric resistance arteries. J Pharmacol Sci. 2008 Mar;106(3):505-11. [3]Mitsuaki Okayama, et al. Protective effect of lafutidine, a novel histamine H2-receptor antagonist, on dextran sulfate sodium-induced colonic inflammation through capsaicin-sensitive afferent neurons in rats. Dig Dis Sci. 2004 Oct;49(10):1696-704.
Smiles	O=C(NC/C=C\COC1=NC=CC(CN2CCCCC2)=C1)CS(CC3=CC=CO3)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	FRG-8813
Available
Product Description	Lafutidine (FRG-8813) is a histamine H2-receptor antagonist (H2RA), with proven gastric mucosal protective effects. Lafutidine can be used for the research of gastroesophageal reflux disease[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	431.55
Clinical Information	Launched
Manufacturers Research Area	Metabolic Disease; Endocrinology
Solubility	DMSO : ≥ 50 mg/mL
Target	Histamine Receptor
Manufacturers Target	Histamine Receptor
Manufacturers Pathway	GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Manufacturers Product type	Reference compound

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HY-B0160-10mg-safety-datasheet.pdf