Item no. |
HY-B0152-10mM |
Manufacturer |
MedChem Express
|
CASRN |
73-24-5 |
Amount |
10mM/1mL |
Quantity options |
10mM/1mL
1 g
500 mg
5 g
|
Category |
|
Type |
Inhibitors |
Specific against |
other |
Purity |
99.98 |
Formula |
C5H5N5 |
Citations |
[1]ORO J, et al. Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide. Arch Biochem Biophys. 1961 Aug;94:217-27.<br/>[2]Griffiths AJF, et al. An Introduction to Genetic Analysis. 7th edition. New York: W. H. Freeman; 2000. Structure of DNA.<br/>[3]Reader V. The assay of vitamin B(4). Biochem J. 1930;24(6):1827-31.<br/>[4]Yung-Jen Tsai, et al. Pharmacokinetics of Adenosine and Cordycepin, a Bioactive Constituent of Cordyceps sinensis in Rat. J Agric Food Chem 2010 Apr 28;58(8):4638-43.<br/>[5]Fatma F Mohamed, et al. Dentoalveolar Alterations in an Adenine‐Induced Chronic Kidney Disease Mouse Model. J Bone Miner Res. 2023 Aug;38(8):1192-1207.<br/>[6]Chien-Ning Hsu, et al. Sodium Thiosulfate Improves Hypertension in Rats with Adenine-Induced Chronic Kidney Disease. Antioxidants (Basel). 2022 Jan 11;11(1):147. |
Smiles |
NC1=C2N=CNC2=NC=N1 |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
Adenine |
Available |
|
Product Description |
Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[1][2][3]. |
StorageTemperature |
-20°C, 3 years; 4°C, 2 years (Powder) |
Shipping |
Room Temperature |
Manufacturers Applications |
Cancer-programmed cell death |
MolecularWeight |
135.13 |
Clinical Information |
Launched |
Manufacturers Research Area |
Cancer |
Solubility |
1M HCl : 20 mg/mL (ultrasonic)|DMSO : ≥ 10 mg/mL|H2O : 2 mg/mL (ultrasonic; warming; heat to 60°C) |
Target |
DNA/RNA Synthesis; Endogenous Metabolite |
Manufacturers Target |
DNA/RNA Synthesis; Endogenous Metabolite |
Isoform |
Human Endogenous Metabolite; Microbial Metabolite |
Manufacturers Pathway |
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease |
Manufacturers Product type |
Natural Products |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.