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Tigecycline

Tigecycline

Item no.	HY-B0117-500mg
Manufacturer	MedChem Express
CASRN	220620-09-7
Amount	500 mg
Quantity options	100 mg 10mM/1mL 10 mg 200 mg 500 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Cell Biology Cell Status Proliferation Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.95
Formula	C29H39N5O8
Citations	Adv Ther (Weinh). 2024 Jan 12.<br/>Animal Diseases. 02 November 2021.<br/>Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00470-19.<br/>Antimicrob Agents Chemother. 2023 Jan 23;e0145922.<br/>Antimicrob Agents Chemother. 2024 Jan 30:e0112023.<br/>Biomed Pharmacother. 2023 Nov 8:115856.<br/>Clin Exp Pharmacol Physiol. 2023 Apr 22.<br/>EBioMedicine. 2022 Apr;78:103943.<br/>Infect Drug Resist. 2020 Jul 28;13:2617-2629.<br/>Infect Drug Resist. 2021 Jun 30;14:2499-2507.<br/>Infect Drug Resist. 2023 Apr 17.<br/>Int J Antimicrob Agents. 2018 Aug;52(2):269-271.<br/>J Antibiot (Tokyo). 2022 Jun 27.<br/>Microb Pathog. 2020 Dec;149:104502.<br/>Microbiol Spectr. 2022 Dec 8;e0323822.<br/>Microbiol Spectr. 2023 May 4;e0071823.<br/>Microorganisms. 2024 Mar 13, 12(3), 575.<br/>Nat Commun. 2022 Mar 2;13(1):1116.<br/>SLAS Discov. 2020 Sep;25(8):895-905.<br/>Vet Microbiol. 2024 May, 292, 110046.<br/>World J Microbiol Biotechnol. 2024 Jun 6;40(8):233.<br/>Ann Lab Med. 2021 May 1;41(3):293-301.<br/>Emerg Microbes Infect. 2024 Dec;13(1):2321981.<br/>[1]Jitkova Y, et al. A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity. PLoS One. 2014 May 28;9(5):e95281.<br/>[2]Falagas ME, et al. Activity of TP-6076 against carbapenem-resistant Acinetobacter baumannii isolates collected from inpatients in Greek hospitals. Int J Antimicrob Agents. 2018 Aug;52(2):269-271.
Smiles	O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=C(NC(CNC(C)(C)C)=O)C=C4N(C)C)N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	GAR-936
Available
Product Description	Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL[1]. MIC50 and MIC90 are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), respectively[2].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	585.65
Clinical Information	Launched
Manufacturers Research Area	Infection; Cancer
Solubility	DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O : 8.33 mg/mL (ultrasonic; warming; heat to 60°C)
Target	Antibiotic; Autophagy; Bacterial
Manufacturers Target	Antibiotic; Autophagy; Bacterial
Manufacturers Pathway	Anti-infection; Autophagy
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-B0117-500mg-safety-datasheet.pdf