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Gabapentin (hydrochloride)

Gabapentin (hydrochloride)

Item no.	HY-A0057A-10mg
Manufacturer	MedChem Express
CASRN	60142-95-2
Amount	10 mg
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category	Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	98.0
Formula	C9H18ClNO2
Citations	Eur J Drug Metab Pharmacokinet. 2022 Jun 22.<br/>ACS Pharmacol Transl Sci. 2023 Mar 6.<br/>Cell Rep. 2019 Dec 17;29(12):3847-3858.e5.<br/>iScience. 2023 Jun 27.<br/>J Nat Med. 2021 Sep 12.<br/>J Pain. 2019 May;20(5):577-591. <br/>Pharmacol Res Perspect. 2021 Oct;9(5):e00879.<br/>Sci Total Environ. 2022 Jul 10;829:154437.<br/>[1]Fink K, et, al. Inhibition of neuronal Ca(2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices. Br J Pharmacol. 2000 Jun;130(4):900-6.<br/>[2]Celikyurt IK, et, al. Gabapentin, A GABA analogue, enhances cognitive performance in mice. Neurosci Lett. 2011 Apr 1;492(2):124-8.<br/>[3]Meymandi MS, et, al. Gabapentin action and interaction on the antinociceptive effect of morphine on visceral pain in mice. Eur J Anaesthesiol. 2008 Feb;25(2):129-34.
Smiles	O=C(O)CC1(CN)CCCCC1.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	60142-95-2
Available
Product Description	Gabapentin hydrochloride is a potent, orally active P/Q type Ca2+ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca2+ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain[1][2][3].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	207.70
Clinical Information	Launched
Manufacturers Research Area	Neurological Disease; Cancer
Solubility	10 mM in DMSO\|H2O : 50 mg/mL (ultrasonic)
Target	Calcium Channel
Manufacturers Target	Calcium Channel
Manufacturers Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-A0057A-10mg-safety-datasheet.pdf