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Carboxypeptidase G2 (CPG2) Inhibitor European Partner

Item no. HY-70003-10mM
Manufacturer MedChem Express
CASRN 192203-60-4
Amount 10mM*1 mL
Quantity options 100 mg 10mM*1 mL 10 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Clone N/A
Specific against other
Purity 98.03
Citations [1]Khan, Tariq H.; Eno-Amooquaye, Ebun A.; Searle, Frances et al. Novel Inhibitors of Carboxypeptidase G2 (CPG2): Potential Use in Antibody-Directed Enzyme Prodrug Therapy. Journal of Medicinal Chemistry (1999), 42(6), 951-956.<br/>[2]Friedlos F, Lehouritis P, Ogilvie L et al. Attenuated Salmonella targets prodrug activating enzyme carboxypeptidase G2 to mouse melanoma and human breast and colon carcinomas for effective suicide gene therapy. Clin Cancer Res. 2008 Jul 1;14(13):4259-66.<br/>[3]Schepelmann S, Ogilvie LM, Hedley D et al. Suicide gene therapy of human colon carcinoma xenografts using an armed oncolytic adenovirus expressing carboxypeptidase G2. Cancer Res. 2007 May 15;67(10):4949-55.<br/>[4]Schepelmann S, Hallenbeck P, Ogilvie LM et al. Systemic gene-directed enzyme prodrug therapy of hepatocellular carcinoma using a targeted adenovirus armed with carboxypeptidase G2. Cancer Res. 2005 Jun 15;65(12):5003-8.
Smiles O=C(SC(C=C1)=CC=C1OC)N[C@@H](CCC(O)=O)C(O)=O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias CPG2 Inhibitor
Available
Product Description
Carboxypeptidase G2 (CPG2) Inhibitor is a novel Carboxypeptidase G2 (CPG2) Inhibitor, Antitumor agents.
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Manufacturers Applications
Cancer-Kinase/protease
MolecularWeight
313.33
Clinical Information
No Development Reported
Manufacturers Research Area
Cancer
Solubility
10 mM in DMSO|H2O : 1.43 mg/mL (ultrasonic)
Target
Carboxypeptidase
Manufacturers Target
Carboxypeptidase
Manufacturers Pathway
Metabolic Enzyme/Protease
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10mM*1 mL
Available: In stock
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