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Vaborbactam

Vaborbactam

Item no.	HY-19930-50mg
Manufacturer	MedChem Express
CASRN	1360457-46-0
Amount	50 mg
Quantity options	100 mg 10mM/1mL 10 mg 1 mg 50 mg 5 mg
Category	Metabolism Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.85
Formula	C12H16BNO5S
Citations	[1]Hecker SJ, et al. Discovery of a Cyclic Boronic Acid β-Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases. J Med Chem. 2015 May 14;58(9):3682-92.<br>[2]Castanheira M, et al. Effect of the β-Lactamase Inhibitor Vaborbactam Combined with SM 7338 against Serine Carbapenemase-Producing Enterobacteriaceae. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5454-8.<br>[3]Wong D, et al. Novel Beta-Lactamase Inhibitors: Unlocking Their Potential in Therapy.
Smiles	O=C(O)C[C@@H]1CC[C@H](NC(CC2=CC=CS2)=O)B(O)O1
ECLASS 5.1	30220300
ECLASS 6.1	30220300
ECLASS 8.0	32160605
ECLASS 9.0	32160605
ECLASS 10.0.1	32160490
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	RPX7009
Available
Product Description	Vaborbactam (RPX7009) is a cyclic boronic acid pharmacophore β-lactamase inhibitor.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	297.14
Clinical_Information	Launched
Manufacturers Research Area	Infection
Solubility	H2O : 5.26 mg/mL (ultrasonic)
Manufacturers Target	Bacterial; Beta-lactamase
Pathway	Anti-infection

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HY-19930-50mg-safety-datasheet.pdf