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MK-0941

MK-0941

Item no.	HY-19843-10mM
Manufacturer	MedChem Express
CASRN	1137916-97-2
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.28
Formula	C22H28N4O9S2
Citations	[1]Eiki J, et al. Pharmacokinetic and pharmacodynamic properties of the glucokinase activator MK-0941 in rodent models of type 2 diabetes and healthy dogs. Mol Pharmacol. 2011 Dec;80(6):1156-65.
Smiles	CS(=O)(O)=O.O=C(NC1=NN(C)C=C1)C2=CC(O[C@@H](C)CO)=CC(OC3=CC=C(S(=O)(CC)=O)N=C3)=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1137916-97-2
Available
Product Description	MK-0941 is a potent, orally active and allosteric glucokinase activator, with EC50s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 has potential in the treatment of type 2 diabetes[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-sugar/lipid metabolism
MolecularWeight	556.61
Clinical Information	Phase 2
Manufacturers Research Area	Metabolic Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	Glucokinase
Manufacturers Target	Glucokinase
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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HY-19843-10mM-safety-datasheet.pdf