DCVC

Item no.	HY-19717-50mg
Manufacturer	MedChem Express
CASRN	13419-46-0
Amount	50 mg
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category	Metabolism Diabetes Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.83
Formula	C5H7Cl2NO2S
Citations	[1]Boldenow E, et al. The trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine but not trichloroacetate inhibits pathogen-stimulated TNF-α in human extraplacental membranes in vitro. Reprod Toxicol. 2015 Apr;52:1-6.<br>[2]Lash LH, et al. Multigenerational study of chemically induced cytotoxicity and proliferation in cultures of human proximal tubular cells. Int J Mol Sci. 2014 Nov 18;15(11):21348-65.
Smiles	N[C@H](C(O)=O)CS/C(Cl)=C\Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	S-[(1E)-1,2-Dichloroethenyl]-L-cysteine
Available
Product Description	DCVC (S-[(1E)-1, 2-Dichloroethenyl]-L-cysteine) is a bioactive metabolite of trichloroethylene (TCE). DCVC inhibits pathogen-stimulated pro-inflammatory cytokines IL-1β, IL-8, and TNF-α release from tissue cultures[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
MolecularWeight	216.09
Clinical_Information	Phase 1
Manufacturers Research Area	Inflammation/Immunology
Solubility	DMSO : 2.5 mg/mL (ultrasonic)\|H2O : 1.034 mg/mL (ultrasonic; warming)
Manufacturers Target	TNF Receptor
Pathway	Apoptosis

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HY-19717-50mg-safety-datasheet.pdf