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BAY-598

BAY-598

Item no.	HY-19546-10mM
Manufacturer	MedChem Express
CASRN	1906919-67-2
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Metabolism Diabetes Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.30
Formula	C22H20Cl2F2N6O3
Citations	[1]Reynoird N, et al. Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreaticcancer. Genes Dev. 2016 Apr 1;30(7):772-85.<br/>[2]Eggert E, et al. Discovery and Characterization of a Highly Potent and Selective Aminopyrazoline-Based in Vivo Probe (BAY-598) for the Protein Lysine Methyltransferase SMYD2. J Med Chem. 2016 May 26;59(10):4578-600.
Smiles	ClC1=C(Cl)C=CC(C2=NN(/C(NC#N)=N/C3=CC=CC(OC(F)F)=C3)C[C@@H]2N(C(CO)=O)CC)=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1906919-67-2
Available
Product Description	BAY-598 is selective small molecule inhibitor of SMYD2 with an IC50 of 27 nM[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	525.34
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 125 mg/mL (ultrasonic)
Target	Histone Methyltransferase
Manufacturers Target	Histone Methyltransferase
Isoform	SMYD2
Manufacturers Pathway	Epigenetics
Manufacturers Product type	Reference compound

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HY-19546-10mM-safety-datasheet.pdf