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(1S,3R,5R)-PIM447 (dihydrochloride)

(1S,3R,5R)-PIM447 (dihydrochloride)

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	10mM*1 mL
Quantity options	10mM*1 mL 10mg 1 mg 50mg 5 mg
Item no.	HY-19322C-10mM
Targets	Pim
eClass 6.1	30220300
eClass 9.0	32160605
Available
Alias	(1S,3R,5R)-LGH447 dihydrochloride
Purity	99.81
Product Description	(1S, 3R, 5R)-PIM447 (dihydrochloride) an PIM inhibitor extracted from patent US 20100056576 A1, compound example 72, has IC50 values of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3.
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	513.38
Clinical_Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 33.33 mg/mL (ultrasonic)\|H2O : 12.5 mg/mL (ultrasonic)
Manufacturers Target	Pim
Isoform	PIM1; PIM2; PIM3
Pathway	JAK/STAT Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-19322C-10mM-safety-datasheet.pdf