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LLY-507

LLY-507

Item no.	HY-19313-10mg
Manufacturer	MedChem Express
CASRN	1793053-37-8
Amount	10 mg
Quantity options	10mM/1mL 10 mg 25 mg 50 mg 5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Bladder Cancer Breast Cancer
Type	Inhibitors
Specific against	other
Purity	98.28
Formula	C36H42N6O
Citations	[1]Nguyen H, et al. LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. J Biol Chem. 2015 May 29;290(22):13641-13653.
Smiles	O=C(C1=CC(C2=CC=CC=C2N3CCN(CCN4C=C(C)C5=C4C=CC=C5)CC3)=CC(C#N)=C1)NCCCN6CCCC6
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1793053-37-8
Available
Product Description	LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase SMYD2. LLY-507 potently inhibits the ability of SMYD2 to methylate p53 peptide with an IC50 [1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	574.76
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 15 mg/mL (ultrasonic; warming)
Target	Histone Methyltransferase
Manufacturers Target	Histone Methyltransferase
Isoform	SMYD2
Manufacturers Pathway	Epigenetics
Manufacturers Product type	Reference compound

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HY-19313-10mg-safety-datasheet.pdf