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Iloperidone (hydrochloride)

Iloperidone (hydrochloride)

Item no.	HY-17410A-50mg
Manufacturer	MedChem Express
CASRN	1299470-39-5
Amount	50mg
Quantity options	100 mg 10mg 1 ea 50mg
Category	Neuroscience Metabolism Regulation of Appetite Neural Signaling Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Kongsamut, S., et al., Iloperidone binding to human and rat dopamine and 5-HT receptors. Eur J Pharmacol, 1996. 317(2-3): p. 417-23.<br>[2]Sainati, S.M., et al., Safety, tolerability, and effect of food on the pharmacokinetics of iloperidone (HP 873), a potential atypical antipsychotic. J Clin Pharmacol, 1995. 35(7): p. 713-20.<br>[3]Albers, L.J., A. Musenga, and M.A. Raggi, Iloperidone: a new benzisoxazole atypical antipsychotic drug. Is it novel enough to impact the crowded atypical antipsychotic market? Expert Opin Investig Drugs, 2008. 17(1): p. 61-75.
Smiles	CC(C1=CC=C(OCCCN2CCC(C3=NOC4=C3C=CC(F)=C4)CC2)C(OC)=C1)=O.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	HP 873 hydrochloride
Available
Product Description	Iloperidone hydrochloride (HP 873 hydrochloride) is a D2/5-HT2 receptor antagonist. Iloperidone hydrochloride is an atypical antipsychotic for the schizophrenia symptoms[1][2].
Shipping	Room temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	462.94
Clinical_Information	Launched
Manufacturers Research Area	Neurological Disease
Solubility	10 mM in DMSO
Manufacturers Target	5-HT Receptor; Dopamine Receptor
Isoform	5-HT1 Receptor; 5-HT2 Receptor; 5-HT6 Receptor; 5-HT7 Receptor; D1 Receptor; D2 Receptor; D3 Receptor; D4 Receptor; D5 Receptor
Pathway	GPCR/G Protein; Neuronal Signaling

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